Fig. 6: TAS1 constitutes a potential therapeutic target in ESCC.

a Images of ex vivo tumors from the ESCC PDX model (n = 5). b, c Tumor volume curve and statistical analysis of the tumor weight of the PDX tumors. d Representative images of H&E staining and immunohistochemical staining for Ki67, TMPO, CyclinD1 and MTA1 in randomly selected PDX tumors from each group. Scale bar, 100 μm. e Statistical analysis of the Ki67 proliferation index (n = 5). f Statistical analysis of the immunohistochemical scores for the indicated genes (n = 5). The data are presented as the mean±S.D. values. *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant.