Fig. 7: AZIN1 editing is common in prostate cancer. | Experimental & Molecular Medicine

Fig. 7: AZIN1 editing is common in prostate cancer.

From: AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer

Fig. 7

a Prostate cancer tissues (Gleason score > 7) were analyzed for wtAZIN and edAZIN mRNA levels by ddPCR. b Analysis of data from primary prostate cancer patients available via The Cancer Genome Atlas (TCGA) for the distribution of AZIN1 editing levels (n = 333). c Correlation between the relative RNA levels of ADAR1 and edited AZIN1 in primary prostate cancer patients from the TCGA cohort (n = 291 with edAZIN1 calls). Frequency of AZIN1 editing in prostate cancer patients stratified by age at cancer diagnosis and genomic instability level (d) and Gleason score (e) (TCGA cohort, n = 333).

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