Fig. 4: STAMBP promotes TNBC progression by regulating RAI14. | Experimental & Molecular Medicine

Fig. 4: STAMBP promotes TNBC progression by regulating RAI14.

From: The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability

Fig. 4

a MDA-MB-231 and BT549 cells stably transfected with STAMBP shRNA #1 or control shRNA were stably expressed with HA-RAI14 or vector. STAMBP and HA-RAI14 expression in cells was measured by Western blotting. b–d Cell proliferation, migration, and invasion of the indicated MDA-MB-231 and BT549 cells were determined by MTS assays (b), wound healing assays (c), and Transwell migration assays (d), respectively. Representative images are shown. Scale bars: 50 μm. The mean ± SD (n = 3). *p < 0.05.

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