Table 1 Morphological features of different types of regulated cell death.

From: Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis

Regulated cell death (RCD)

Morphological Features

Lysis

Membrane rupture

Pore formation

Cell swelling

Organelle swelling

Cell shrinkage

Membrane blebbing

Chromatin condensation

DNA damage

Intact nucleus

Pyroptosis

√

√

√

√

Χ

Χ

√

√

√

√

Apoptosis

Χ

Χ

Χ

Χ

Χ

√

√

√

√

Χ

Necroptosis

√

√

√

√

√

Χ

Χ

Χ

√

√

PANoptosis

√

√

√

√

√

√

√

√

√

√

  1. The table shows the morphological features of pyroptosis, apoptosis, necroptosis, and PANoptosis.