Table 1 Morphological features of different types of regulated cell death.
Regulated cell death (RCD) | Morphological Features | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Lysis | Membrane rupture | Pore formation | Cell swelling | Organelle swelling | Cell shrinkage | Membrane blebbing | Chromatin condensation | DNA damage | Intact nucleus | |
Pyroptosis | √ | √ | √ | √ | Χ | Χ | √ | √ | √ | √ |
Apoptosis | Χ | Χ | Χ | Χ | Χ | √ | √ | √ | √ | Χ |
Necroptosis | √ | √ | √ | √ | √ | Χ | Χ | Χ | √ | √ |
PANoptosis | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ |