Fig. 7: Off-target analyses in myoblasts.
From: Precise base editing without unintended indels in human cells and mouse primary myoblasts

a, b Identification of off-target (OT) effects at the DNA level for CBE and ABE variants in myoblasts on day 10 of transfection. c, d Off-target analyses at the mRNA level for CBE and ABE variants in myoblasts on day 10 of transfection. Control indicates the untreated group. The data are shown as the mean ± S.D. of three independent replicates. Each dot indicates an individual experiment.