Fig. 3: RNA sequencing data for cancer formation and 5-FU chemotherapy-induced mouse tissues.

a Scheme for analyzing RNA sequencing differences between PBS and DH groups in a CT26-engrafted mouse model. b A Volcano plot depicting differential gene expression between vehicle control mice and mice treated with DH. c–f GO enrichment analysis of the significantly differentially expressed genes in DH-treated tumor-bearing mice versus vehicle-treated nontumor-bearing mice. c GO cellular component and d biological process pathways associated with upregulated genes. e GO cellular component and f biological process pathways associated with downregulated genes. DH dimenhydrinate.