Fig. 9: Schematic depiction of the Epinephrine-ADRB2-c-Myc-USP10-PLAGL2 interaction in HCC cells.

Schematic representation showing how stress-induced epinephrine increases the expression of PLAGL2 through the ADRB2-c-Myc-USP10 signaling axis to promote the metastasis and progression of HCC.