Fig. 1: The secondary and tertiary structures mediate the various functions of regulatory RNAs.
From: Molecular insights into regulatory RNAs in the cellular machinery
The dynamic structure of RNA is simply classified as the secondary a tertiary structures formed by specific base pairing and numerous factors, and various RNAs affect biological functions via these structures. In regulatory RNAs, the secondary structure is related to gene silencing via miRNA expression, miRNA maturation, and RNA modifications via scaRNAs. The tertiary structure participates in the regulation of p53 and the differential expression of miRNAs and mRNAs.
