Fig. 3: Illustration of a peripheral nerve and reported phenotypes described in inherited peripheral neuropathies (IPNs) using iPSCs. | Experimental & Molecular Medicine

Fig. 3: Illustration of a peripheral nerve and reported phenotypes described in inherited peripheral neuropathies (IPNs) using iPSCs.

From: Advances and challenges in modeling inherited peripheral neuropathies using iPSCs

Fig. 3

The schematic shows different phenotype terms, numbered and located within the neuron based on the reported IPN iPSC studies. These terms can then be broadly divided into the following categories: neuronal defects, mitochondrial dysfunction, Schwann cell, metabolic and protein abnormalities, inflammation, and immune response. Created with BioRender.com.

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