Fig. 1: YAP1 expression is decreased in AT2 cells during pulmonary fibrosis. | Experimental & Molecular Medicine

Fig. 1: YAP1 expression is decreased in AT2 cells during pulmonary fibrosis.

From: YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis

Fig. 1

a, b Bioinformatics analysis of the expression of YAP1 in AT1 cells, AT2 cells and fibroblasts from healthy donors and IPF patients (GSE135893). c, d Representative images showing YAP1 (red), Sftpc (green), S100A4 (green) and nuclei (blue) in lung sections from mice treated with saline or BLM. Scale bars, 10 μm. e Western blot analysis of YAP1 expression in MLE-12 cells after BLM induction; n = 6. f qRT‒PCR analysis of YAP1 mRNA expression in MLE-12 cells treated with BLM; n = 5. The data are presented as the means ± SEMs. **P < 0.01.

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