Fig. 2: Transcriptomic profile of tRCC.
From: Comprehensive molecular characterization of TFE3-rearranged renal cell carcinoma
a PCA plot of RCC and normal tissues. b Volcano plot, c Heatmap, d GO profiles, and e GSEA results obtained using DEGs in tRCC and ccRCC samples. f Pathways enriched with genes upregulated in tRCC. g Analysis of the master regulators of the DEGs. PCA principal component analysis, tRCC translocation renal cell carcinoma, ccRCC clear cell renal cell carcinoma, GO Gene Ontology, GSEA gene set enrichment analysis, DEGs differentially expressed genes, NES normalized enrichment score, TNFSF tumor necrosis factor superfamily, IL interleukin, TCA tricarboxylic acid, FC fold change.
