Fig. 6: L-BAIBA suppresses PANoptosis in a rat model.

a Schematic diagram for detecting PANoptosis in SD rats. b Respective immunohistochemical staining of apoptosis markers (C-CAS3), pyroptosis markers (NLRP3, C-GSDMD) and necrosis markers (p-MLKL) in the three groups (CTR, AFP and AFP + L-BAIBA). Scale bar: 20 μm. c Semiquantitative and statistical analyses of immunohistochemical staining for apoptosis markers (C-CAS3), pyroptosis markers (NLRP3, C-GSDMD) and necrosis markers (p-MLKL). d Representative immunofluorescence images of apoptosis markers (C-CAS3), pyroptosis markers (C-GSDMD) and necrosis markers (p-MLKL). Scale bar: 200 μm. The data are shown as the means ± SDs; *p < 0.05.