Fig. 2: QD-expressing microglia exhibit local distribution near the injection sites.
From: Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
a Representative IF images of the ipsilateral striatum labeled with an antibody specific for Iba1 3 months after injection of activated microglia pretreated with QDs. Scale bar, 30 μm. b–e The proportion of QD-expressing microglia in the ipsilateral striatum 3 days (b), 7 days (c), 1 month (d) and 3 months (e) after injection. All data are presented as the mean ± s.e.m. Statistical significance was determined by one-way ANOVA with Tukey’s post hoc test. f Representative IF images of the brain regions labeled with an antibody specific for Iba1 3 months after injection of activated microglia pretreated with QDs. Scale bar, 50 μm. IST, ipsilateral striatum distal to injection area; CST, contralateral striatum; ICX, ipsilateral motor cortex; CCX, contralateral motor cortex.
