Fig. 1: Correlations of FAIM2 expression with fatty liver diseases. | Experimental & Molecular Medicine

Fig. 1: Correlations of FAIM2 expression with fatty liver diseases.

From: Fas apoptotic inhibitor molecule 2 mitigates metabolic dysfunction-associated fatty liver disease through autophagic CRTC2 degradation

Fig. 1

a,b Western blot images and normalized quantification of FAIM2 expression in the livers of C57BL/6J mice that were fed a HFD or NC for 24 weeks (n = 4) (a) or mice that were fed a HFHC or NC for 16 weeks (n = 4) (b). c Western blot images and normalized quantification of FAIM2 expression from individuals with nonsteatotis, individuals with fatty liver (MAFL) and individuals with MASH (n = 4). d Western blot images and normalized quantification of FAIM2 expression in primary hepatocytes treated with palmitate and oil acid (PAOA, PA:OA = 0.5 mM:1 mM) (n = 3). e Images of FAIM2 immunofluorescence staining of primary hepatocytes treated with PBS or PAOA. Scale bars, 20 μm. f,g Western blot images and normalized quantification of FAIM2 expression in endothelial cells treated with PAOA (f) or Kupffer cells treated with LPS (g) (n = 3). **P < 0.01; n.s., not significant. The data were expressed as the means ± s.d. Statistical analysis was carried out via one-way ANOVA or two-tailed Student’s t-test.

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