Fig. 13: Inflammation induction and correlation with the autophagy process in WT and MPS IIIB mice.
From: TFEB, FOXO3 and TLR4 in resveratrol-induced autophagy in a mucopolysaccharidosis IIIB mouse model
a, b Top: the levels of IRAK1 and pIRAK1 (a) and AMPKα (b) protein in the brains of male mice shown as either relative to the loading control or the ratio of phosphorylated to total protein. Bottom: representative western blots with statistical analysis in the brains of male mice. c, d Top: the levels of IRAK1 and pIRAK1 (c) and AMPKα (d) protein in the brains of female mice shown as either relative to the loading control or the ratio of phosphorylated to total protein. Bottom: representative western blots with statistical analysis in the brains of female mice. The results are shown as mean values ± s.d. (n = 6–7). Statistically significant differences are indicated by asterisks: *P< 0.05, **P< 0.01 and ****P < 0.0001.
