Fig. 20: Sirtuin and FOXO activation by resveratrol in the brain of WT and MPS IIIB mice.
From: TFEB, FOXO3 and TLR4 in resveratrol-induced autophagy in a mucopolysaccharidosis IIIB mouse model
a Representative western blots of P-SIRT1 and SIRT1 protein levels in the brain of male mice shown as the ratio of phosphorylated to total protein. b Representative western blots of P-FOXO3 and FOXO3 protein levels in the brain of male mice shown as the ratio of phosphorylated to total protein. c Representative western blots of P-SIRT1 and SIRT1 protein levels in the brain of female mice shown as the ratio of phosphorylated to total protein. d Representative western blots of P-FOXO3 and FOXO3 protein levels in the brain of female mice shown as the ratio of phosphorylated to total protein. The results are shown as mean values ± s.d. (n = 6–7). Statistically significant differences are indicated by asterisks: ***P < 0.001 and ****P < 0.0001.
