Fig. 3 | International Journal of Obesity

Fig. 3

From: Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers

Fig. 3

Insulin signaling in the liver of subjects with normal liver and NAFLD. The expression of insulin receptor substrates-2 (IRS-2) is decreased, while the expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) are increased in patients with NAFLD. In contrast, the expression of IRS-1 is unaltered and the expression of fatty acid synthase (FAS) is increased in patients with NAFLD

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