Fig. 4 | International Journal of Obesity

Fig. 4

From: Maternal overnutrition programs epigenetic changes in the regulatory regions of hypothalamic Pomc in the offspring of rats

Fig. 4

Glucose homeostasis in the adult male offspring. a Intraperitoneal glucose tolerance test (IPGTT) at 8 weeks (Student’s t-test, n = 7) and c at 19 weeks of age (two-way ANOVA: postweaning diet effect at t0, P = 0.0436; t15, ‡‡P = 0.0077; t90, P = 0.0168, n = 8) in the offspring of LF- or HF-fed dams. b,d homeostatic model assessment indices of insulin resistance (HOMA-IR) in the offspring of LF- or HF-fed dams at week 8 (D-LF, n = 5; D-HF, n = 6) and at week 19 (two-way ANOVA: maternal diet effect, P = 0.0495, n = 5, ηp2 = 0.22). Data are shown as mean ± SEM. *P < 0.05

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