Table 1 Clinical characteristics and circulating cytokine levels of the study participants
From: Periodontitis affects glucoregulatory hormones in severely obese individuals
PD+ (n = 47) | PD− (n = 63) | p value | |
|---|---|---|---|
Age (years) | 48 ± 7 | 48 ± 12 | 0.910 |
Sex (F/M) | 28/19 | 37/26 | 0.950 |
SBP (mmHg) | 130.6 ± 18.9 | 130.1 ± 16.1 | 0.896 |
DBP (mm) | 85.9 ± 10.6 | 83.1 ± 11.0 | 0.245 |
BMI (kg/m2) | 41.4 ± 8.7 | 47.1 ± 8.3 | 0.001 |
Waist (cm) | 116.1 ± 10.3 | 132.1 ± 11.7 | 0.001 |
Fasting plasma glucose (mmol/l) | 5.37 ± 1.29 | 5.09 ± 1.23 | 0.100 |
Fasting plasma insulin (pmol/l) | 90.29 [49.27] | 80.97 [91.33] | 0.075 |
HOMA-IR | 3.38 [2.41] | 2.71 [3.58] | 0.05 |
Total cholesterol (mmol/l) | 5.29 ± 1.13 | 5.02 ± 0.96 | 0.182 |
Triglycerides (mmol/l) | 1.64 ± 0.83 | 1.61 ± 0.80 | 0.850 |
HDL cholesterol (mmol/l) | 1.21 ± 0.35 | 1.26 ± 0.36 | 0.473 |
Metabolic syndromea (%) | 52 | 48 | 0.932 |
hs CPR (mg/l) | 4.31 ± 3.80 | 3.67 ± 2.62 | 0.290 |
IL-6 (pg/ml) | 4.45 [2.10] | 1.99 [1.34] | < 0.0001 |
IL-1β (pg/ml) | 3.53 [3.32] | 1.99 [1.88] | 0.002 |
TNFα (pg/ml) | 2.82 [2.03] | 2.03 [1.27] | 0.003 |