Fig. 3
From: Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents
Linear regression analysis to test the association of the combined insulin sensitivity-increasing and WHRadjBMI-decreasing genetic score with adiposity and cardiometabolic variables in normal weight (white column) and overweight/obese (black column) children and adolescents as beta values (standard errors) of the inverse normally transformed traits. The results are aligned according to the insulin sensitivity-increasing/WHRadjBM-decreasing allele of the genetic score. All analyses are adjusted for age, sex, puberty, and first three genome-wide principal components. The effects were pooled using fixed effects models meta-analysis. *P-values <0.05. The numerical values for betas, standard errors, p-values, and the number of subjects are presented in Supplementary Tables 5–6
