Table 3 Rates of patients with adverse events by weight groups (normal weight, overweight, obese) and all patients. MACE is defined as death or nonfatal myocardial infarction or nonfatal stroke.
Normal weight group treated (n = 26) | Normal weight group untreated control (n = 37) | p value between groups | Overweight group treated (n = 121) | Overweight group untreated control (n = 165) | p value between groups | Obese group treated (n = 281) | Obese group untreated control (n = 193) | p value between groups | ALL Treated (n = 428) | ALL Untreated control (n = 395) | p value between groups | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Deaths | 1 (3.8%) | 3 (8.1%) | NS | 4 (3.3%) | 14 (8.5%) | NS | 18 (6.4%) | 60 (31.1%) | <0.0001 | 23 (5.4%) | 77 (19.5%) | <0.0001 |
Nonfatal myocardial infarctions | 0 (0%) | 4 (10.8%) | NS | 0 (0%) | 21 (12.7%) | <0.0001 | 0 (0%) | 49 (25.4%) | <0.0001 | 0 (0%) | 74 (18.7%) | <0.0001 |
Nonfatal strokes | 0 (0%) | 6 (16.2%) | <0.05 | 0 (0%) | 11 (6.7%) | <0.005 | 0 (0%) | 50 (25.9%) | <0.0001 | 0 (0%) | 67 (17.0%) | <0.0001 |
Prostate cancer | 0 (0%) | 1 (2.7%) | NS | 5 (4.1%) | 15 (9.1%) | NS | 7 (2.5%) | 29 (15.0%) | <0.0001 | 12 (2.8%) | 45 (11.4%) | <0.05 |
MACE | 1 (3.9%) | 8 (21.6%) | NS | 4 (3.3%) | 38 (23.0%) | <0.0001 | 18 (6.4%) | 98 (50.8) | <0.0001 | 23 (5.4%) | 144 (36.5%) | <0.0001 |
