Table 2 Factors showing significant or borderline significant association with placental inositol.

From: High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

Categorical variable

Unadjusted β (95% CI) placental inositol z-score (SDs)

P value

Adjusted β (95% CI)a placental inositol z-score (SDs)

P value

Tobacco smoke exposure

    

 No

Reference

 

Reference

 

 Yes

0.22 (0.08, 0.36)

0.002

0.24 (0.08, 0.40)

0.003

Mode of delivery

    

 Non-labour caesarean section

Reference

 

Reference

 

 Intrapartum caesarean section

−0.11 (−0.36, 0.14)

0.388

−0.15 (−0.44, 1.35)

0.299

 Vaginal delivery

−0.21 (−0.41, −0.14)

0.036

−0.29 (−0.52, −0.06)

0.013

Timing of placental collection after delivery (minutes)

    

 ≤30

Reference

 

Reference

 

 31–60

−0.18 (−0.39, 0.03)

0.094

−0.18 (−0.41, 0.05)

0.133

 61–90

−0.30 (−0.54, −0.06)

0.013

−0.29 (−0.55, −0.02)

0.033

 ≥91

−0.35 (−0.63, −0.07)

0.013

−0.22 (−0.53, 0.08)

0.148

Continuous variable

Unadjusted β (95% CI) Placental inositol SDs/unit increase

P value

Adjusted β (95% CI)a Placental inositol SDs/unit increase

P value

2hPG (mmol/L)

−0.05 (−0.10, −0.01)

0.021

−0.06 (−0.12, −0.01)

0.028

Gestational age at birth (days)

0.01 (0, 0.02)

0.026

0.01 (0, 0.03)

0.008

  1. 2hPG 2-hour plasma glucose.
  2. aAdjusted for maternal age, ethnicity, parity, pre-pregnancy BMI, neonatal sex, and mutually adjusted for tobacco smoke exposure, gestational age, mode of delivery, timing of placental collection after delivery, and 2hPG at mid-gestation.