Table 5 Participant characteristics across the placental inositol tertile groups.

From: High placental inositol content associated with suppressed pro-adipogenic effects of maternal glycaemia in offspring: the GUSTO cohort

 

Groups of placental inositol tertiles

 

Lowest

Middle

Highest

P valuea

Inositol z-score, range

−3.337, −0.470

−0.469, 0.336

0.337, 3.990

 

Maternal age (years)

30.9 ± 5.0

31.2 ± 5.2

31.3 ± 4.9

0.590

Ethnicity

   

0.601

 Chinese

171 (58.0)

183 (62.0)

176 (59.9)

 Non-Chinese

124 (42.0)

112 (38.0)

118 (40.1)

Parity

   

0.400

 Nulliparous

138 (46.8)

126 (42.7)

122 (41.5)

 Parous

157 (53.2)

169 (57.3)

172 (58.5)

Pre-pregnancy BMI (kg/m2)

22.5 ± 4.6

22.6 ± 4.1

22.3 ± 3.9

0.690

Tobacco smoke exposure

   

0.167

 No

163 (55.3)

153 (51.9)

134 (45.6)

 Yes

103 (34.9)

117 (39.7)

128 (43.5)

 Missing

29 (9.8)

25 (8.5)

32 (10.9)

Gestational age at birth (weeks)

39.0 ± 1.0

39.1 ± 1.0

39.2 ± 1.0

0.090

Neonatal sex

   

0.745

 Male

152 (51.5)

161 (54.6)

158 (53.7)

 Female

143 (48.5)

134 (45.4)

136 (46.3)

Mode of delivery

   

0.137

 Non-labour caesarean section

32 (10.9)

41 (13.9)

44 (15)

 Intrapartum caesarean section

38 (12.9)

55 (18.6)

44 (15)

 Vaginal delivery

225 (76.3)

199 (67.5)

206 (70.1)

Timing of placental collection after delivery (minutes)

   

0.116

 ≤30

33 (11.2)

31 (10.5)

46 (15.7)

 31–60

132 (44.8)

150 (50.9)

151 (51.4)

 61–90

56 (19.0)

56 (19.0)

48 (16.3)

 ≥91

37 (12.5)

31 (10.5)

21 (7.1)

 Missing

37 (12.5)

27 (9.2)

28 (9.5)

GDM (WHO 1999 criteria)

   

0.053

 No

218 (73.9)

234 (79.3)

239 (81.3)

 Yes

64 (21.7)

47 (15.9)

43 (14.6)

 Missing

13 (4.4)

14 (4.8)

12 (4.1)

GDM Treatment

   

0.941

 Diet-only

57 (20.2)

42 (15.0)

38 (13.5)

 Insulin

4 (1.4)

3 (1.1)

4 (1.4)

 None

3 (1.1)

2 (0.7)

1 (0.4)

FPG (mmol/L)

4.3 ± 0.5

4.4 ± 0.5

4.3 ± 0.4

0.069

2hPG (mmol/L)

6.6 ± 1.5

6.5 ± 1.4

6.4 ± 1.4

0.226

  1. Data presented as mean ± SD or n (%).
  2. BMI body mass index, FPG fasting plasma glucose, GDM gestational diabetes mellitus, 2hPG 2-hour plasma glucose.
  3. aChi-squared test (for categorical variables) and Fisher’s exact test (for categorical variables with cells having an expected frequency of five or less) were used to analyse categorical data. One-way ANOVA was used to compare the means across groups.