Fig. 2: Clearance of 13C-labeled FFA in placentae of lean versus obese women. | International Journal of Obesity

Fig. 2: Clearance of 13C-labeled FFA in placentae of lean versus obese women.

From: Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity

Fig. 2

Direct transfer of 13C-labeled A palmitic acid (16:0), B oleic acid (18:1), C linoleic acid (18:2n6), and D docosahexaenoic acid (22:6n3) was determined in lean (n = 7) and obese (n = 6) placentae by ex vivo perfusion. Kinetic of FFA transfer was investigated utilizing a closed (recirculated) maternal and open (nonrecirculating) fetal circulation. Mean (± SD) 13C-FFA clearance was calculated at time points 0, 10, 20, 30, 60, and 90 min. Two-way ANOVA and Bonferroni post hoc test were performed, one experiment in each group was excluded from the analysis due to missing FFA measurements at one single time point, * p < 0.05, ** p < 0.01, and *** p < 0.001.

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