Fig. 1: Direct effects of genetically predicted body mass index (BMI) and genetically predicted waist-to-hip ratio (WHR) on coronary artery disease (CAD), peripheral artery disease (PAD) and stroke, estimated after adjusting for genetic liability to mediators separately and together in the same model. | International Journal of Obesity

Fig. 1: Direct effects of genetically predicted body mass index (BMI) and genetically predicted waist-to-hip ratio (WHR) on coronary artery disease (CAD), peripheral artery disease (PAD) and stroke, estimated after adjusting for genetic liability to mediators separately and together in the same model.

From: Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

Fig. 1

The y-axis details the genetically predicted mediator(s) for which adjustments were made. Blood pressure refers to systolic blood pressure. Lipids refer to serum low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides considered together in one model. CI confidence interval, OR odds ratio, SD standard deviation.

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