Fig. 2: Proportion (as a percentage) of the respective effects of genetically predicted body mass index (BMI) and genetically predicted waist-to-hip ratio (WHR) on coronary artery disease (CAD), peripheral artery disease (PAD) and stroke that are mediated through the genetically predicted risk factors individually and together.
The y-axis details the genetically predicted mediator(s) for which adjustment was made. Blood pressure refers to systolic blood pressure. Lipids refer to serum low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides considered together in one model. CI confidence interval.
