Table 2 Comparison of outcomes of second pregnancy among BMI stable (reference group, OR = 1), reduced and increased interpregnancy BMI.

From: Does interpregnancy BMI change affect the risk of complications in the second pregnancy? Analysis of pooled data from Aberdeen, Finland and Malta

Outcomes of 2nd pregnancy

BMI stable

Reduced BMI

Increased BMI

n = 118,924 (72.7%)

n = 9,438 (5.8%)

n = 35,126 (21.5%)

n (%)

n (%)

Unadjusted

Adjusted

n (%)

Unadjusted OR (95% CI)

Adjusted ORa (95% CI)

OR (95% CI)

OR (95% CI)

   

PE

3,519 (3.0%)

340 (3.6%)

1.23 (1.09–1.37)

1.12 (0.99–1.26)

1,786 (5.1%)

1.76 (1.66–1.86)

1.66 (1.49–1.86)

Placenta praevia

726 (0.6%)

66 (0.7%)

1.15 (0.89–1.48)

1.22 (0.95–1.58)

206 (0.6%)

0.96 (0.82–1.12)

1.09 (0.91–1.30)

Placental abruption

336 (0.3%)

35 (0.4%)

1.31(0.93–1.86)

1.33 (0.93–1.91)

100 (0.3%)

1.01 (0.81–1.26)

0.91 (0.70–1.18)

IUGR

2,607 (2.2%)

254 (2.7%)

1.24 (1.09–1.41)

1.15 (1.01–1.31)

601 (1.7%)

0.78 (0.71–0.85)

0.94 (0.85–1.04)

Preterm birth

<37 weeks

3,229 (2.7%)

297 (3.1%)

1.16 (1.03–1.32)

1.14 (1.01–1.30)

1,025 (2.9%)

0.93 (0.86–1.00)

0.96 (0.88–1.04)

<34 weeks

693 (0.6%)

71 (0.8%)

1.30 (1.02–1.66)

1.33 (1.04–1.72)

210 (0.6%)

0.97 (0.83–1.14)

0.99 (0.83–1.18)

<32 weeks

262 (0.2%)

27 (0.3%)

1.30 (0.88–1.96)

1.15 (0.75–1.75)

89 (0.3%)

0.87 (0.68–1.10)

0.90 (0.68–1.18)

Birthweight

       

Low <2500 g

2,700 (2.3%)

248 (2.6%)

1.16 (1.02–1.33)

1.12 (0.97–1.28)

791 (2.3%)

0.99 (0.92–1.07)

1.05 (0.96–1.16)

High ≥4000 g

21,094 (17.7%)

1,619 (17.2%)

0.96 (0.91–1.02)

0.93 (0.87–0.98)

8,004 (22.8%)

1.37 (1.33–1.41)

1.06 (1.03–1.10)

 Stillbirth

227 (0.2%)

20 (0.2%)

1.11 (0.70–1.76)

1.13 (0.70–1.81)

88 (0.3%)

1.31 (0.93–1.68)

1.14 (0.85–1.53)

Mode of delivery

       

Instrumental

6,029 (5.1%)

365 (3.9%)

0.78 (0.69–0.86)

0.75 (0.68–0.85)

1,746 (5.0%)

0.97 (0.91–1.02)

0.96 (0.90–1.03)

Elective CS

8,276 (7.0%)

825 (8.7%)

1.29 (1.18–1.37)

0.96 (0.88–1.05)

3,267 (9.3%)

0.71 (0.68–0.74)

0.96 (0.91–1.01)

Emergency CS

7,454 (6.3%)

657 (7.0%)

1.12 (1.04–1.22)

1.03 (0.94–1.13)

2,962 (8.4%)

0.70 (0.67–0.74)

0.97 (0.92–1.02)

  1. Statistically significant odds ratios (p < 0.001) are shown as bold.
  2. aAll odds ratios are adjusted for maternal age, BMI, smoking, social class, marital status, interpregnancy interval, country of origin, year of delivery at the second pregnancy. In addition, models were adjusted for the same outcome in the previous pregnancy. Low and high birthweight was also adjusted for gestational age at delivery preterm birth was additionally adjusted for induction of labour.