Table 1 Analysis of covariance looking at the overall effect of the combined BMI/WHR group on the volumes of subcortical regions-of-interest before and after adjustment for total GM volume.
Region of interest | Hemisphere | Results adjusted for covariates | Results adjusted for GM atrophy and covariates | ||||||
|---|---|---|---|---|---|---|---|---|---|
F (5, 15,619) | p value | ηp2 | F (5, 15,619) | p value | ηp2 | ||||
Thalamus | Left | 6.618 | 3.658 × 10−6 | 0.002 | * | 4.461 | 4.606 × 10−4 | 0.001 | * |
Thalamus | Right | 7.056 | 1.345 × 10−6 | 0.002 | * | 4.921 | 1.672 × 10−4 | 0.001 | * |
Caudate | Left | 5.98 | 1.559 × 10−5 | 0.001 | * | 5.235 | 8.306 × 10−5 | 0.001 | * |
Caudate | Right | 6.943 | 1.741 × 10−6 | 0.002 | * | 6.164 | 1.027 × 10−5 | 0.002 | * |
Putamen | Left | 2.752 | 0.017 | 0.001 | 1.695 | 0.131 | 5.43 × 10−4 | ||
Putamen | Right | 2.668 | 0.02 | 8.542 × 10−4 | 1.478 | 0.193 | 0.0004 | ||
Pallidum | Left | 7.238 | 8.838 × 10−7 | 2.314 × 10−3 | * | 7.24 | 8.798 × 10−7 | 2.315 × 10−4 | * |
Pallidum | Right | 10.244 | 8.074 × 10−10 | 0.003 | * | 9.356 | 6.489 × 10−9 | 0.002 | * |
Amygdala | Left | 2.751 | 0.017 | 8.81 × 10−4 | 2.733 | 0.018 | 0.001 | ||
Amygdala | Right | 3.804 | 0.001 | 0.001 | * | 3.626 | 0.0028 | 0.001 | * |
Nucleus accumbens | Left | 8.4318 | 5.606 × 10−8 | 0.002 | * | 4.886 | 1.805 × 10−4 | 0.001 | * |
Nucleus accumbens | Right | 9.884 | 1.882 × 10−9 | 0.003 | * | 5.676 | 3.098 × 10−5 | 0.001 | * |
Hippocampus | Left | 0.927 | 0.461 | 2 × 10−3 | 0.586 | 0.071 | 1.88 | ||
Hippocampus | Right | 2.546 | 0.026 | 0.001 | 2.563 | 0.025 | 0.001 | ||
