Table 3 Partial correlations between indicators of body composition derived from abdominal MRI and neuroimaging outcomes adjusted for covariates.

From: Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank

Abdominal MRI

Brain MRI

r

CI 95%

Adjusted variance explained

p value

Significant

Visceral adipose tissue volume

Brain volume

−0.072

[−0.1, −0.05]

0.00486

1.928×10−07

*

GM volume

−0.096

[−0.12, −0.07]

0.00888

4.279×10−12

*

WM volume

0.023

[0.05, 0.0]

0.00018

0.085

 

Global efficiency

−0.011

[−0.02, 0.04]

0.00031

0.441

 

Local efficiency

−0.018

[−0.01, 0.05]

0.0001

0.217

 

Abdominal subcutaneous adipose tissue volume

Brain volume

−0.067

[−0.09, −0.04]

0.00419

0.000001

*

GM volume

−0.094

[−0.12, −0.07]

0.0085

1.178×10−11

*

WM volume

−0.018

[−0.05, 0.01]

0.00004

0.184

 

Global efficiency

0.015

[−0.01, 0.05]

0.00019

0.289

 

Local efficiency

0.01

[−0.02, 0.04]

0.00034

0.498

 

Total adipose tissue volume

Brain volume

−0.112

[−0.13, −0.09]

0.012

2.679×10−21

*

GM volume

−0.08

[−0.1, −0.06]

0.00614

1.157×10−11

*

WM volume

−0.021

[−0.04, 0.0]

0.00016

0.075

 

Global efficiency

0.006

[−0.02, 0.03]

0.00028

0.649

 

Local efficiency

3E-04

[−0.02, 0.02]

0.0003

0.979

 

Lean tissue volume (normalized by body weight)

Brain volume

0.048

[0.03, 0.07]

0.002

0.00004

*

GM volume

0.046

[0.02, 0.07]

0.001878

0.000093

*

WM volume

0.032

[0.01, 0.06]

0.000762

0.0065

*

Global efficiency

0.005

[−0.02, 0.03]

0.000283

0.649

 

Local efficiency

3E−04

[−0.02, 0.02]

0.000316

0.979

 
  1. Significant results, at the p = 0.05 level, are shown in bold and with *.