Fig. 4: Effects of familial obesity risk to central glucose uptake and μ-opioid receptor availability. | International Journal of Obesity

Fig. 4: Effects of familial obesity risk to central glucose uptake and μ-opioid receptor availability.

From: Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability

Fig. 4

a Brain regions where higher Family Risk score associated with increased brain glucose uptake in the 38 individuals studied with [18F]FDG. b Brain regions where higher Family Risk score associated with lower μ-opioid receptor availability in the 41 individuals studied with [11C]carfentanil. The effects of familial obesity risk we global for brain glucose uptake, whereas the associations were most prominent in striatum and insula for μ-opioid receptors. The images show results from SnPM13 linear regression, with age and other risk factors (BMI, physical exercise) as covariates. The data are thresholded at p < 0.05, FWE corrected at cluster level.

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