Fig. 1: Melatonin secretion in regards to patients’ characteristics.

A Shows differences of melatonin secretion in boys and girls. B Shows melatonin secretion in regards to different pubertal stages. Comparison of nocturnal melatonin secretion in patients without and with insulin resistance (C). Data are presented as boxplots. For statistical analysis Mann–Whitney U Test (A, C) and Kruskal–Wallis-Test (B) with Bonferroni correction was performed *p < 0.05; **p < 0.01.