Table 1 Patients’ characteristics.

From: Interactions between nocturnal melatonin secretion, metabolism, and sleeping behavior in adolescents with obesity

 

All (n = 149)

Without IR (n = 46)

With IRd (n = 101)

p-value

Clinical characteristics

Sex (n; %)

 Male

71 (48%)

21 (46%)

48 (48%)

0.833e

 Female

78 (52%)

25 (54%)

53 (52%)

 

Age (years)b

14.7(12.8–16.3)

14.5 (12.1–16.1)

15.1 (13.3–16.3)

0.415e

Pubertal stage (n; %)c

 Prepubertal (I)

13 (10%)

6 (15%)

6 (6%)

0.293e

 Pubertal (II,III)

27 (20%)

8 (20%)

19 (21%)

 

 Postpubertal (IV,V)

94 (70%)

26 (65%)

67 (73%)

 

BMI (kg/m²)b

31.9 (29.5–37.2)

29.2 (27.7–32.0)

34.6 (30.7–38.9)

<0.001

BMI-SDSa

2.7 ± 0.6

2.4 ± 0.5

2.9 ± 0.5

<0.001

Systolic RR (mmHg)b

132 (122–141)

129 (120–138)

133 (126–142)

0.094

Diastolic RR (mmHg)b

68 (63–73)

68 (62–72)

68 (64–73)

0.684

Chemical analysis

Triglycerides (mg/dl)b

93 (69–129)

69 (58–96)

102 (77–144)

<0.001

Total cholesterol (mg/dl)b

162 (147–184)

160 (138–179)

163 (152–186)

0.087

HDL cholesterol (mg/dl)b

48 (40–55)

53 (43–61)

46 (39–53)

0.001

LDL cholesterol (mg/dl)b

98 (85–117)

93 (73–111)

99 (86–119)

0.044

Uric Acid (mg/dl)b

5.5 (4.8–6.7)

5.2 (4.2–6.7)

5.7 (4.9–6.7)

0.050

MT6s:Cr ratiob

27.4 (17.2–37.4)

32.6 (23.0–44.0)

26.4 (15.8–35.0)

0.006

  1. Bold values identify statistical significance p < 0.05.
  2. BMI body mass index, BMI-SDS BMI standard deviation score, HDL high-density lipoprotein, IR insulin resistance, LDL low-density lipoprotein, RR Riva-Rocci blood pressure, MT6s 6-sulfatoxymelatonin, Cr creatinine.
  3. aData shown as mean ± SD.
  4. bData shown as median (25.–75.percentile).
  5. cPubertal stages (Tanner), n = 15 missing.
  6. ddefined as HOMA-IR > 95th percentile: according to Allard et al. [40]; n = 2 missing.
  7. eχ2-Test.
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