Fig. 2: Effects of prenatal exposures on rapid postnatal growth through cord blood metabolites. | International Journal of Obesity

Fig. 2: Effects of prenatal exposures on rapid postnatal growth through cord blood metabolites.

From: Cord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight

Fig. 2

The plots represent on the x-axis the (log) point estimates odds ratio (dots) and 95% confidence intervals (bars) from single mediation analysis (N = 375) for the effects of a maternal low vs high education, b one kilogram increase of maternal weight during the pregnancy, c one week increase of gestation, and d primiparous vs pluriparous on the rapid postnatal growth through the metabolites—grouped in five sets: metabolites previously related with rapid growth (rg), overweight (ov), and rapid growth and overweight (rg and ov) in the MWAS, and metabolites previously related with rapid growth (rg*) and overweight (ov*) in the look-up analyses of Handakas et al. [18]. All the analyses are adjusted for sex of the newborns, child ethnicity and cohort membership. The analyses of maternal weight gain, gestational age and parity are additionally adjusted for maternal education, pre-pregnancy BMI, smoking, age at delivery, and parity. CI: confidence intervals, NIE: natural indirect effect; NDE: natural direct effect; OR: odds ratio; TE: total effect.

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