Fig. 3: Adjusted hazard ratios of mortality by percentiles of body mass index, fasting insulin, and c-reactive protein.

BMI body mass index, CRP c-reactive protein These hazards ratios are adjusted for body mass index (a quadratic and linear term), fasting insulin (a linear term), c-reactive protein (natural logarithm term), age, biological sex, smoking status, and ten chronic conditions (angina, arthritis, cancer, chronic heart failure, chronic liver disease, chronic lung disease, coronary artery disease, diabetes, stroke, and thyroid problems). The black marker represents the referent at the 5th percentile for all three exposures of interest. In this primary cohort, 1342 (10.7%) of participants died.