Fig. 1: Acute transcriptomic exercise response in subcutaneous adipose tissue (Fat) biopsies of participants that underwent an 8-week training intervention program.

Transcriptomic changes were calculated to assess the acute exercise effects (n = 8) and the long-term training (n = 9) effects as compared to the baseline untrained state. A Volcano plot depicting up- and down-regulated transcripts in fat after acute exercise in an untrained state. Transcripts with FC ≥ 1.2 and limma t-test with BH correction at FDR < 10% were considered significantly regulated (red). Top 5 regulated transcripts based on FC were labeled. B Enrichment analysis of significantly regulated transcripts in fat after acute exercise in an untrained state (FC ≥ 1.2 and limma t-test p < 0.01). C Volcano plot depicting up- and down-regulated transcripts in fat after 8 weeks of training in a rested state FC ≥ 1.2 and limma t-test p < 0.01. D Enrichment analysis of significantly regulated transcripts in fat after training (FC ≥ 1.2 and limma t-test p < 0.01). Shown are significantly enriched terms.