Table 2 Multiple linear regression analysis on HOMA-IR in cohort A.

From: Identification of circulating apolipoprotein M as a new determinant of insulin sensitivity and relationship with adiponectin

R2 = 39

 

β estimate

SE

P-value

%b

ApoM

−0.133

0.045

0.0035

5.6

Waist circumferencea

0.177

0.046

0.0002

13.6

γ-GTa

0.181

0.046

0.0001

9.6

ApoC-IIIa

1.421

0.044

0.0016

4.5

Diabetes

0.353

0.132

0.0084

2.8

  1. Variables at entry: Adiponectin, apoC-III, apoB-100, apoM, BMI, γ-GT, hs-CRP, HDL-C, physical activity, triglycerides, waist circumference, diabetes (fasting blood glucose ≥7.0 mmol/L or treatment vs. no), dyslipidemia (total cholesterol ≥2.50 g/L or treatment), hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg or treatment) and case-control status. Continuous variables were standardized. β estimates were given for one standard deviation variation. n = 169.
  2. ApoB-100 apolipoprotein B100, ApoC-III apolipoprotein C-III, ApoM apolipoprotein M, BMI body mass index, γ-GT gamma-glutamyltransferase, HDL-C high-density lipoprotein cholesterol, hs-CRP high-sensitivity C-Reactive Protein, HOMA-IR Homeostasis Model Assessment of Insulin Resistance, LDL-C low-density lipoprotein cholesterol.
  3. aLog-transformed data.
  4. bPercentage of variance explained.