Fig. 1: Effect of weight loss on metabolic outcomes in C57BL/6 J mice.
From: The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity
a Weight loss study design, (b–g) metabolic outcomes at 16 wk time point including (b) fat mass, (c) fasting insulin, (d) insulin at 15 min time point during glucose tolerance test (GTT) (e) fasting glucose, (f) GTT results and area under the GTT curve, (g) ex-vivo 2-deoxyglucose (2DG) uptake basal (0 nM) and insulin stimulated (10 nM) into adipose tissue. Error bars are SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs AOb (n = 6–16/group). All statistical analysis was conducted using ANOVA. WL: Weight loss, AOb: Always having Obesity.
