Fig. 2: Segmented coronal fat images of two female participants at baseline and follow-up showing less VAT loss in a woman with more SAT in the lower third at baseline (participant A) compared to more VAT loss in a woman with fewer SAT in the lower third at baseline (participant B).

VAT is marked in green, and SAT is marked in blue. The upper left image shows the concept of division into equidistant thirds (upper, middle, lower third). Participant A (female, 49 years, baseline BMI 32.1 kg/m²) with a SAT distribution with emphasis in the lower third (0.43 L/cm) lost 12.62% VAT after the 8-week calorie restriction. Participant B (female, 56 years, baseline BMI 32.2 kg/m²) with a more balanced SAT distribution with less SAT in the lower third (0.39 L/cm) lost 31.45% VAT after the 8-week calorie restriction. The biggest change in SAT is visible in the lower third of the segmented region in both participants. SAT (blue) subcutaneous adipose tissue, VAT (green) visceral adipose tissue.