Table 3 Unadjusted and multivariate analysis adjusted mean difference (95% CI) for sex hormones between baseline and 36 months per 1 kg weight loss.
From: Sex-differential testosterone response to long-term weight loss
Parameter | Univariate analysis | Multivariate analysisa |
|---|---|---|
Trend estimate (kg/36 months; 95% CI) | ||
Females | ||
Testosterone | −0.8% (−1.4% to −0.3%) | −0.9% (−1.4% to −0.3%) |
SHBG | 0.5% (0.0% to 0.9%) | 0.4% (−0.1% to 0.9%) |
LH | 0.8% (−0.1% to 1.6%) | −0.1% (−0.7% to 0.6%) |
FSH | 1.3% (0.3% to 2.3%) | 0.1% (−0,6% to 0.7%) |
Oestradiol | 0.2% (−0.5% to 0.9%) | 0.4% (−0.2 to 0.1%) |
Males | ||
Testosterone | 0.6% (0.2% to 1.0%) | 0.7% (0.3% to 1.1%) |
SHBG | 0.4% (0.0% to 0.8%) | 0.4% (0.0% to 0.7%) |
CFT | 0.5% (0.0 to 0.9%) | 0.7% (0.3% to 1.1%). |
LH | 0.2% (−0.2% to 0.6%) | 0.1%(−0.5% to 0.3%) |
FSH | 0.5% (0.% to 1.0%) | 0.6% (0.1% to 1.1%) |
Oestradiol | 0.1% (−0.3% to 0.5%) | 0.2% (−0.1% to 0.6%) |
All participants | ||
ACTH | 0.2% (−0.1% to 0.4%) | −0.3% (0% to −0.5%) |
Cortisol | 0.1% (−0.2% to 0.3%) | 0.1% (−0.1% to 0.3%) |
IGF1 | 0.4% (0.1% to 0.6%) | 0.4% (0.2% to 0.7%) |
TSH | 0% (−0.4% to 0.5) | 0.1% (−0.4% to 0.6%) |
FT4 | −0.2% (0 to −0.3%) | −0.2% (0% to −0.3%) |
FT3 | −0.1% (0% to −0.2%) | −0.1% (0% to −0.2%) |
