Table 3 Contributing factors to BMI, waist circumference and metabolic syndrome in 103 adults with 22q11.2 deletion syndrome.

From: Obesity and metabolic syndrome in adults with a 22q11.2 microdeletion

 

BMI

WCa

MetS

B

SE B

β

t

Pb

B

SE B

β

t

Pb

OR

95% CI

Pb

Age at last assessment

0.10

0.05

0.21

2.00

<0.05

0.51

0.13

0.39

3.92

<0.001

1.07

1.03

1.12

<0.001

Female sex

1.07

1.25

0.08

0.86

0.39

−4.71

3.31

−0.13

−1.42

0.16

1.44

0.55

3.78

0. 46

Congenital heart disease

−2.44

1.30

−0.19

−1.88

0.06

−5.58

3.44

−0.16

−1.62

0.11

1.19

0.44

3.24

0.74

Smoking

1.62

1.54

0.10

1.05

0.30

3.62

4.09

0.08

0.89

0. 38

1.80

0.62

5.28

0.28

Antipsychotic medication

0.25

1.36

0.02

0. 81

0.86

0.02

3.61

0.00

0.01

1.00

0.72

0.26

2.01

0.53

  1. Standard multiple regression analyses were performed to examine the independent associations between demographic and clinical factors, and BMI and WC. In addition, a logistic regression analysis was performed to identify the variables predictive of MetS.
  2. BMI body mass index, WC waist circumference, MetS metabolic syndrome, B unstandardized coefficient, SE standard error, ß standardized coefficient, OR odds ratio, CI confidence interval.
  3. an = 98; five patients had no data for WC.
  4. bBold font indicates statistical significance.