Fig. 2: Glucose homeostasis in male and female Angptl2-KD and control mice on STD or HFD.

Glycemia in male (A–C) and female (D–F) Angptl2-KD mice (vs. WT controls) during an ITT after 16 weeks of STD vs. HFD. A, D Fasting glycemia, B, E glycemia during insulin tolerance test (ITT) and C, F total AUC of glycemia during ITT in WT and Angptl2-KD mice. N = 7–10 mice per group; Two-way ANOVA (genotype X diet); Sidak’s post hoc test. *p < 0.05 Angptl2-KD vs. WT mice; ‡p < 0.05 HFD vs. STD.