Table 3 Association between weight loss and 3-year changes in inflammatory biomarkers.

	C-reactive protein (n = 515)			Interleukin-6 (n = 515)			GlycA (n = 454)			Total adiponectin (n = 509)
	Beta ± SE	RD	P	Beta ± SE	RD	P	Beta ± SE	RD	P	Beta ± SE	RD	P
No weight loss	reference			reference			reference			reference
<5% weight Loss	−0.102 ± 0.048	−21.0	0.034	−0.051 ± 0.035	−11.0	0.15	−0.011 ± 0.011	−2.5	0.295	0.044 ± 0.017	10.8	0.009
5−10% weight loss	−0.200 ± 0.051	−36.9	<0.001	−0.086 ± 0.037	−17.9	0.021	−0.014 ± 0.011	−3.1	0.207	0.096 ± 0.018	24.7	<0.001
>10% weight loss	−0.392 ± 0.052	−59.5	<0.001	−0.175 ± 0.038	−33.1	<0.001	−0.034 ± 0.011	−7.5	0.003	0.186 ± 0.018	53.5	<0.001

SE standard error, RD relative difference.
RD can be interpreted as a percent lower (negative value) or higher (positive value).
Models were adjusted by age (years), sex (male vs. female), race (White vs. non-White), education (years), APOE e4 carriership (yes vs. no), body mass index (kg/m²), physical activity (hours/week), smoking history (never vs. ever), MIND diet score (points), and dietary assignment (MIND diet group vs control diet group).

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