Fig. 2: Changes in IWQOL-Lite-CT scores by percent-weight-loss categories: <5%, 5–9.9%, ≥10%.

A Epitomee treatment arm (n = 119). B Placebo treatment arm (n = 121). Within-group analyses showed significantly greater changes compared to baseline for Epitomee and placebo groups (#p < 0.05). In the Epitomee group, all change scores were significantly smaller for participants who lost <5% of their weight compared to those who lost ≥10% (*p < 0.05, **p < 0.01), whereas in the placebo group, this was observed only for the Psychosocial score (*p < 0.05).