Fig. 3 | International Journal of Oral Science

Fig. 3

From: Local icariin application enhanced periodontal tissue regeneration and relieved local inflammation in a minipig model of periodontitis

Fig. 3

Histopathological assessments of periodontal tissue regeneration. HE staining shows new periodontal tissue regeneration in the periodontal lesions in the 0.9% NaCl group (a, c, e) and icariin group (b, d, f). HE staining reveals new cementum and Sharpey’s fibres in the 0.9% NaCl group (c, e) and icariin group (d, f). g, h Quantitative analyses of new cementum. Scale bar = 2 mm (a, b), 100 μm (c, d), 25 μm (e, f). Red arrow, inflammatory cells; Green arrow, Sharpey’s fibres; Black arrow, cementoblast; White bar = the width of new cementum. Bars and vertical lines: means ± standard deviations. Student’s t test was used to detect statistical significance. **P < 0.01. ICA, icariin; CEJ, cementoenamel junction; HAB, height of the alveolar bone; NC, new cementum; PDL, periodontal ligament

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