Table 2 Proteases detected in saliva from patients with various oral diseases
Item | Healthy | JBO | CPD | OSCC |
---|---|---|---|---|
ADAM8 | ADAM8 | ADAM8 | ||
ADAM9 | ADAM9 | |||
ADAMTS1 | ADAMTS1 | |||
ADAMTS13 | ||||
Cathepsin A | Cathepsin A | Cathepsin A | Cathepsin A | |
Cathepsin B | Cathepsin B | Cathepsin B | Cathepsin B | |
Cathepsin C | Cathepsin C | Cathepsin C | Cathepsin C | |
Cathepsin D | Cathepsin D | Cathepsin D | Cathepsin D | |
Cathepsin E | ||||
Positive proteases | Cathepsin S | Cathepsin S | Cathepsin S | Cathepsin S |
Cathepsin V | Cathepsin V | Cathepsin V | Cathepsin V | |
Cathepsin X/Z/P | Cathepsin X/Z/P | Cathepsin X/Z/P | Cathepsin X/Z/P | |
DPPIV/CD26 | DPPIV/CD26 | DPPIV/CD26 | DPPIV/CD26 | |
Kallikrein 5 | Kallikrein 5 | Kallikrein 5 | Kallikrein 5 | |
Kallikrein 6 | Kallikrein 6 | Kallikrein 6 | Kallikrein 6 | |
Kallikrein 7 | Kallikrein 7 | |||
Kallikrein 10 | Kallikrein 10 | Kallikrein 10 | Kallikrein 10 | |
Kallikrein 11 | Kallikrein 11 | Kallikrein 11 | Kallikrein 11 | |
Kallikrein 13 | Kallikrein 13 | Kallikrein 13 | Kallikrein 13 | |
MMP-1 | ||||
MMP-2 | ||||
MMP-3 | ||||
MMP-7 | MMP-7 | |||
MMP-8 | MMP-8 | MMP-8 | MMP-8 | |
MMP-9 | MMP-9 | MMP-9 | MMP-9 | |
MMP10 | ||||
MMP-12 | MMP-12 | |||
MMP-13 | ||||
Neprilysin/CD10 | Neprilysin/CD10 | |||
uPA/Urokinase | uPA/Urokinase | |||
Proprotein convertase 9 | Proprotein convertase 9 | Proprotein convertase 9 | ||
Proteinase 3 | Proteinase 3 | Proteinase 3 | ||
Total | 17(48.6%) | 18(51.4%) | 25(71.4%) | 30(85.7%) |