Fig. 4 | International Journal of Oral Science

Fig. 4

From: Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain

Fig. 4

The expression of p-MAPKs on SGCs in vitro after vehicle administration and 24 h after SP and L703, 606 administration. a–c IF staining of p-MAPKs in the vehicle and SP groups. (green: p-ERK1/2, p-P38, and p-JNK; red: GS; blue: DAPI). Scale bars: 100 μm. WB images and graphs in d–f show the quantification of p-ERK1/2, p-P38 and p-JNK expression levels in vehicle-, SP- and SP+L703, 606-treated SGCs for 24 h. SP pretreatment upregulated the expression of p-MAPKs in SGCs, and L703,606 abolished the effect of SP. (n = 6, *P < 0.05 compared with the vehicle group, #P < 0.05 compared with SP group)

Back to article page