Fig. 2
From: FACEts of mechanical regulation in the morphogenesis of craniofacial structures
Branchial arch elongation. In the developing mandibular arch, Wnt5a acts upstream of YAP and Piezo1 to control cell polarity and cortical tension oscillations in the middle segment of the arch. This results in increased cell intercalation and tissue fluidity, driving arch elongation. In comparison, the distal arch is stiffer as a result of reduced cell movement and increased deposition of fibronectin
