Fig. 2 | International Journal of Oral Science

Fig. 2

From: Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells

Fig. 2

P. gingivalis induced mitochondrial dysfunction in endothelial cells. EA.hy926 cells were treated with P. gingivalis (MOI = 100) for the indicated amounts of time. a Mitochondrial ROS (mtROS) levels were determined by MitoSOX Red staining and confocal laser scanning microscopy. Scale bars: 50 µm. b The mitochondrial membrane potential (MMP) was measured by JC-1 staining and confocal laser scanning microscopy. Scale bars: 50 µm. c Quantification of mtROS levels via flow cytometry. d Quantitative of the MMP by flow cytometry. e Quantitative analysis of ATP production. The results were obtained from three independent experiments. *P < 0.05 vs the control

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