Fig. 2

Quantitative immunostaining of osteocytes in the alveolar bone between the tooth roots of the first molar and cementocytes in the mesial root of the first molar in male (left) and female (right) WT and Hyp mice treated with vehicle or Scl-Ab. a, g Quantitative measurements of the percentage of nonphosphorylated β-catenin-stained osteocytes normalized by the total number of bone-embedded osteocytes within the alveolar bone region of interest. b, h Osteopontin stained osteocytes. c, i DMP1-stained osteocytes. d, j nonphosphorylated β-catenin-stained cementocytes. e, k Osteopontin stained cementocytes (f, l) DMP1-stained cementocytes. Data are presented as the mean ± standard deviation. Results from the two-way analysis of variance (ANOVA) are presented in the figure legends. Significant post hoc treatment differences between animals of the same genotype are presented as a horizontal bar. P value thresholds are indicated with stars above the bars: *P < 0.05; **P < 0.01; ***P < 0.001. The sample sizes ranged between 3 and 6 samples per group