Table 1 Immunohistochemical of WNT7A stain in 137 cases of HNSCC tissues

From: WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling

Characteristics

Cases

WNT7A(Low)

WNT7A(High)

P value

Cancer VS Normal

Cancer

137

62

75

<0.001

Normal

137

126

11

***

Gender

Male

93

38

55

0.132 9

Female

44

24

20

 

Age

Less than 60

87

42

45

0.348 8

60 and up

50

20

30

 

Tumor Stages

T1 and T2

58

28

30

0.604 6

T3 and T4

79

34

45

 

Differentiation

Well

83

44

39

0.023 7

Poorly or Moderately

54

18

36

*

WPOI-5

Present

27

9

18

0.164 8

Not Identified

110

53

57

 

Perineural Invasion

Present

52

16

36

0.007 7

Not Identified

85

46

39

**

Extra nodal extension

Present

21

9

12

0.810 4

Not Identified

116

53

63

 

Lymph Node Metastasis

N0

92

44

48

0.387 4

N1 and N2

45

18

27