Table 1 Immunohistochemical of WNT7A stain in 137 cases of HNSCC tissues
Characteristics | Cases | WNT7A(Low) | WNT7A(High) | P value |
|---|---|---|---|---|
Cancer VS Normal | ||||
Cancer | 137 | 62 | 75 | <0.001 |
Normal | 137 | 126 | 11 | *** |
Gender | ||||
Male | 93 | 38 | 55 | 0.132 9 |
Female | 44 | 24 | 20 | |
Age | ||||
Less than 60 | 87 | 42 | 45 | 0.348 8 |
60 and up | 50 | 20 | 30 | |
Tumor Stages | ||||
T1 and T2 | 58 | 28 | 30 | 0.604 6 |
T3 and T4 | 79 | 34 | 45 | |
Differentiation | ||||
Well | 83 | 44 | 39 | 0.023 7 |
Poorly or Moderately | 54 | 18 | 36 | * |
WPOI-5 | ||||
Present | 27 | 9 | 18 | 0.164 8 |
Not Identified | 110 | 53 | 57 | |
Perineural Invasion | ||||
Present | 52 | 16 | 36 | 0.007 7 |
Not Identified | 85 | 46 | 39 | ** |
Extra nodal extension | ||||
Present | 21 | 9 | 12 | 0.810 4 |
Not Identified | 116 | 53 | 63 | |
Lymph Node Metastasis | ||||
N0 | 92 | 44 | 48 | 0.387 4 |
N1 and N2 | 45 | 18 | 27 | |